Recurrent pregnancy loss is defined as any case history including two or more unsuccessful pregnancies.
Around 80,000 people per year experience this.
In the case of three or more such events, the phrase “habitual pregnancy loss” is used.
In Japan, it is reported that the frequency of Non-Developing Syndrome is about 6%, and the frequency for recurring miscarriages is about 1.5% (Sugiura-Ogasawara M, et al. Live birth rate according to maternal age and previous number of recurrent miscarriages. Am J Reprod Immunol 2009; 62: 314-319.).
While chemical pregnancies are not technically considered miscarriage or pregnancy loss, if there are multiple chemical pregnancies, we wish to investigate it similarly.
Beginning of implantation |
Submerge |
Hormone secretion |
Pregnancy reaction |
Completion of implantation |
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Implantation begins when the embryo is attached to the endometrial epithelial cells.
The fertilized oocyte will immediately submerge itself into the endometrium.
From this stage, the pregnancy will be established.